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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPA2
All Species:
19.09
Human Site:
T148
Identified Species:
30
UniProt:
Q9H2U2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2U2
NP_001029363.1
334
37920
T148
N
Y
G
T
L
P
Q
T
W
E
D
P
H
E
K
Chimpanzee
Pan troglodytes
XP_001164495
327
36742
D156
T
G
C
C
G
D
N
D
P
I
D
V
C
E
I
Rhesus Macaque
Macaca mulatta
XP_001082969
325
36595
T148
N
Y
G
T
L
P
Q
T
W
E
D
P
G
E
K
Dog
Lupus familis
XP_535679
303
34598
S148
E
I
G
S
K
V
L
S
C
G
E
V
I
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q91VM9
330
38096
H148
P
Q
T
W
E
D
P
H
L
R
D
K
S
T
D
Rat
Rattus norvegicus
NP_001129343
330
37824
K150
T
W
E
D
P
H
L
K
D
K
S
T
N
C
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420502
467
51453
T278
N
Y
G
A
L
P
Q
T
W
E
D
P
N
H
T
Frog
Xenopus laevis
NP_001084935
304
34676
T148
E
I
G
S
K
V
C
T
R
G
D
V
I
Q
V
Zebra Danio
Brachydanio rerio
NP_001017833
291
32624
V136
K
V
C
S
R
G
D
V
I
K
V
K
V
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O77460
338
37921
T150
N
Y
G
A
L
P
Q
T
W
E
N
P
D
H
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18680
407
44134
T223
N
Y
G
A
L
P
Q
T
W
E
D
P
N
H
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O48556
214
24351
K59
N
V
V
V
E
I
T
K
G
S
K
V
K
Y
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXC9
300
33362
N145
K
L
R
Y
Y
P
Y
N
I
N
W
N
Y
G
L
Baker's Yeast
Sacchar. cerevisiae
P00817
287
32281
T132
I
G
E
T
I
A
Y
T
G
Q
V
K
Q
V
K
Red Bread Mold
Neurospora crassa
Q6MVH7
290
32621
G135
G
E
L
V
G
Y
T
G
Q
V
K
Q
V
K
V
Conservation
Percent
Protein Identity:
100
50.9
91.3
78.1
N.A.
75.4
73.6
N.A.
N.A.
47.5
57.1
54.4
N.A.
45.2
N.A.
38.3
N.A.
Protein Similarity:
100
67
92.8
84.7
N.A.
84.1
83.5
N.A.
N.A.
56.9
72.1
67.9
N.A.
60.9
N.A.
52.8
N.A.
P-Site Identity:
100
13.3
93.3
6.6
N.A.
6.6
0
N.A.
N.A.
73.3
20
0
N.A.
66.6
N.A.
73.3
N.A.
P-Site Similarity:
100
13.3
93.3
26.6
N.A.
6.6
20
N.A.
N.A.
80
33.3
13.3
N.A.
73.3
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
23.3
N.A.
34.4
44.6
42.2
Protein Similarity:
N.A.
40.4
N.A.
50
58.3
58
P-Site Identity:
N.A.
6.6
N.A.
6.6
20
0
P-Site Similarity:
N.A.
13.3
N.A.
13.3
33.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
0
7
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
14
7
0
0
7
0
7
0
0
0
7
7
7
% C
% Asp:
0
0
0
7
0
14
7
7
7
0
47
0
7
0
7
% D
% Glu:
14
7
14
0
14
0
0
0
0
34
7
0
0
20
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
14
47
0
14
7
0
7
14
14
0
0
7
7
7
% G
% His:
0
0
0
0
0
7
0
7
0
0
0
0
7
20
0
% H
% Ile:
7
14
0
0
7
7
0
0
14
7
0
0
14
0
14
% I
% Lys:
14
0
0
0
14
0
0
14
0
14
14
20
7
7
20
% K
% Leu:
0
7
7
0
34
0
14
0
7
0
0
0
0
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
40
0
0
0
0
0
7
7
0
7
7
7
20
0
0
% N
% Pro:
7
0
0
0
7
40
7
0
7
0
0
34
0
7
0
% P
% Gln:
0
7
0
0
0
0
34
0
7
7
0
7
7
7
0
% Q
% Arg:
0
0
7
0
7
0
0
0
7
7
0
0
0
0
0
% R
% Ser:
0
0
0
20
0
0
0
7
0
7
7
0
7
0
0
% S
% Thr:
14
0
7
20
0
0
14
47
0
0
0
7
0
7
7
% T
% Val:
0
14
7
14
0
14
0
7
0
7
14
27
14
7
27
% V
% Trp:
0
7
0
7
0
0
0
0
34
0
7
0
0
0
0
% W
% Tyr:
0
34
0
7
7
7
14
0
0
0
0
0
7
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _